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Peptide Therapy with sermorelin is designed to stimulate the body’s natural production and release of growth hormone. Treatment may help support the maintenance of lean muscle and bone health, reduce visceral abdominal fat, and support sleep, recovery, and overall well-being.
Peptide Therapy Consultation
Contents
About the Treatment
A Comprehensive, Individualized Approach
Peptide therapy at Refyne Medical Aesthetics and Wellness begins with a comprehensive medical consultation rather than simply prescribing a peptide based on a patient’s goals. Dr. Brooklyn Buras, DNP, APRN, FNP-BC will review the patient’s medical history, current medications and supplements, symptoms, sleep, changes in body composition, exercise and lifestyle habits, previous peptide or hormone use, and individual treatment goals.
An important part of the consultation is education. Patients learn how the body’s natural growth hormone pathway works, how sermorelin stimulates the pituitary gland to release naturally occurring growth hormone, and how growth hormone subsequently influences downstream physiologic processes. We also discuss realistic treatment expectations, potential risks and side effects, proper administration, and how treatment will be monitored over time.
Comprehensive Laboratory Evaluation & Monitoring
Baseline laboratory testing is performed as part of our medical evaluation before treatment. A particularly important component of sermorelin therapy is evaluation of IGF-1, which provides a clinically measurable marker related to activity of the growth hormone axis. Because growth hormone itself is released in pulses and fluctuates throughout the day, a random growth hormone measurement is generally not useful for assessing growth hormone status. IGF-1 provides a more stable marker, although it must be interpreted in clinical context and is not, by itself, diagnostic of growth hormone deficiency.
Additional laboratory testing is selected according to the patient’s medical history, medications, symptoms, and treatment goals. Results are interpreted alongside the patient’s clinical presentation rather than using a single laboratory value to determine treatment.
Once therapy begins, IGF-1 and other clinically appropriate markers can be monitored over time, allowing treatment to be evaluated using both the patient’s clinical response and objective laboratory information. Monitoring IGF-1 is particularly relevant because excessive activation of the GH/IGF-1 axis carries potential risks.
- Individualized peptide therapy. When sermorelin is appropriate for you, your dose is chosen based on your labs, symptoms, age, and goals, then adjusted over time based on your IGF-1 levels and clinical response.
- Medication pick-up and injection training. At a dedicated pick-up visit, you receive your medication and one-on-one training on small subcutaneous injections. Sermorelin is typically injected at bedtime, when the body naturally releases the most growth hormone.
- Ongoing follow-up. Regular follow-up visits review your sleep, energy, recovery, body composition, side effects, and labs, so your plan evolves with your response.
What Does Peptide Therapy Address?
Sermorelin therapy may be appropriate for adults experiencing age-related changes linked to declining growth hormone activity. These include increased abdominal fat, reduced lean muscle, poor sleep quality, slower recovery from exercise, lower energy, and changes in skin quality. By supporting the body’s own growth hormone release rather than replacing the hormone directly, sermorelin works within the body’s natural feedback system. Research on sermorelin for age-related concerns is more limited than for FDA-approved therapies, and results vary between individuals.
Who Is a Candidate?
Candidates are generally healthy adults with age-related changes in body composition, sleep, or recovery who have been evaluated and have appropriate baseline labs. Sermorelin is not appropriate for people with active cancer or a history of certain cancers, and it is not appropriate during pregnancy or breastfeeding. It may also be unsuitable with untreated thyroid disease, uncontrolled diabetes, or known sensitivity to the medication. Patients who are mainly focused on significant weight loss may be better served by medical weight loss. Hormone-related symptoms may call for a hormone evaluation instead or in addition.
The Peptide Therapy Consultation
Your first visit covers your health history, medications and supplements, sleep, exercise, body composition changes, prior peptide or hormone use, and goals. Baseline labs, including IGF-1, are drawn. At a results visit, your provider explains your labs, discusses realistic expectations and risks, and confirms whether sermorelin is a good fit.
What to Expect During Treatment
Sermorelin is given as a small injection under the skin, usually in the abdomen, at home on your prescribed schedule. The needle is very fine, and most patients find the injections easy and quick after their training visit.
Recovery and Aftercare
There is no downtime. Possible side effects include redness or tenderness at the injection site, flushing, headache, and dizziness. These are usually mild. Rotate injection sites and report any persistent or unusual symptoms to your provider.
Results
Some patients notice better sleep and recovery within the first few weeks. Changes in body composition, such as less abdominal fat and more lean muscle, typically take 3 to 6 months. Results vary with age, baseline labs, sleep, nutrition, exercise, and consistency. Benefits depend on continued therapy together with healthy habits.
Why Choose Refyne for Peptide Therapy?
Refyne treats peptide therapy as medical care. Every patient receives a full consultation, baseline labs, and education before starting. IGF-1 is monitored for both effectiveness and safety. Your provider is a board-certified Family Nurse Practitioner with a primary care background, and peptide therapy can be coordinated with hormone care and medical weight loss in one plan.
FAQ
What is sermorelin?
Sermorelin is a peptide that signals the pituitary gland to release your body’s own growth hormone.
Is sermorelin the same as growth hormone?
No. It stimulates your natural release of growth hormone instead of replacing it directly.
Why is IGF-1 tested?
IGF-1 is a stable marker of growth hormone activity. It is used to guide dosing and monitor safety.
How is it taken?
As a small injection under the skin, usually at bedtime.
When will I notice results?
Sleep and recovery may improve within weeks. Body composition changes usually take 3 to 6 months.
Are there risks or side effects?
Injection-site reactions, flushing, and headache are the most common. Your provider reviews your specific risks at your consultation.
Can it be combined with other treatments?
Yes. It is often combined with hormone therapy or medical weight loss when appropriate.